2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Acetolactate Synthase (ALS)

Acetolactate Synthase (ALS)

Acetohydroxyacid synthase

Acetohydroxyacid synthase (ALS), a thiamine diphosphate-dependent enzyme, can condense either two pyruvate molecules to form acetolactate for synthesizing Lvaline and L-leucine or pyruvate with 2-ketobutyrate to form acetohydroxybutyrate for synthesizing L-isoleucine. Because the key reaction catalyzed by acetohydroxyacid synthase in the biosynthetic pathways of branched-chain amino acids (valine, leucine, and isoleucine) exists in plants, fungi, archaea, and bacteria, but not in animals, acetohydroxyacid synthase becomes a potential target for developing novel herbicides and antimicrobial compounds.

Acetolactate Synthase (ALS) Related Products (40):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100427
    Imazamox
    		99.78%
    Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.
    Imazamox
  • HY-119737
    Chlorsulfuron
    		99.95%
    Chlorsulfuron blocks the biosynthesis of the amino acids valine and isoleucine in plants. Chlorsulfuron completely alleviates herbicide-induced growth inhibition. The site of action of Chlorsulfuron is the enzyme acetolactate synthase.
    Chlorsulfuron
  • HY-B1847
    Terbuthylazine
    		98.0%
    Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide. Terbuthylazine blocks electron transport in photosystem II via interaction with the D1-protein.
    Terbuthylazine
  • HY-B0869A
    Bispyribac sodium
    		99.56%
    Bispyribac sodium is a selective, orally active, systemic and post-emergence herbicide. Bispyribac sodium reduces SOD levels and inhibits ALS activity. Bispyribac sodium blocks the biosynthesis of branched-chain amino acids, resulting in growth retardation, chlorosis and necrosis of weeds. Bispyribac sodium exerts herbicidal activity against grass, sedge and broadleaf weeds in rice fields. Bispyribac sodium is hepatotoxic and genotoxic.
    Bispyribac sodium
  • HY-B1876
    Nicosulfuron
    Nicosulfuron is efficient, harmless, antifungal and selective herbicide belonging to the sulfonylurea family. Nicosulfuron is also a photosynthetic system inhibitor and inhibits acetolactate synthase (ALS) enzyme activity. Nicosulfuron degradation by Plectosphaerella cucumerina AR1 is glucose concentration dependent in planktonic lifestyle. Nicosulfuron enhances the glycolysis pathway and tricarboxylic acid cycle to improve the adaptability of sweet maize. Nicosulfuron reduces the synthesis of branched-chain amino acids (BCAAs), which is proming for maize cultivation.
    Nicosulfuron
  • HY-178732
    AB-22
    		Inhibitor
    AB-22, a vinyl sulfate compound, is an orally active antifungal agent. AB-22 inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in Candida albicans SC5314 cells. AB-22 can be used for the research of infrction, such as systemic candidiasis.
    AB-22
  • HY-111670
    α-Acetohydroxybutyric acid
    		Substrate
    α-Acetohydroxybutyric acid is a metabolic intermediate produced under the catalysis of acetolactate synthase. α-Acetohydroxybutyric acid is generated from 2-oxobutyric acid and converted into 2,3-dihydroxy-3-methylpentanoic acid in the 2-methylbutanol biosynthetic pathway.
    α-Acetohydroxybutyric acid
  • HY-W040206
    Diflufenican
    		99.77%
    Diflufenican is a Herbicide. Diflufenican inhibits phytoene desaturase (PDS) in the carotenoid synthesis pathway. Diflufenican suppresses the production of PDS, blocks carotenoid biosynthesis, thereby inducing chlorophyll destruction and cell membrane rupture, and ultimately causes the death of broadleaf weeds. The combination of Diflufenican and Flufenacet can be used to control Lolium rigidum populations resistant to ALS/ACCase.
    Diflufenican
  • HY-100427R
    Imazamox (Standard)
    Imazamox (Standard) is the analytical standard of Imazamox. This product is intended for research and analytical applications. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.
    Imazamox (Standard)
  • HY-B0865
    Pyrazosulfuron-ethyl
    		98.42%
    Pyrazosulfuron-ethyl, one of the acetolactate synthase inhibiting herbicides in the sulphonylurea family, has been widely used to control weed growth in commercial cereal, soybean, and vegetable fields.
    Pyrazosulfuron-ethyl
  • HY-B1847S
    Terbuthylazine-d9
    Terbuthylazine-d9 is the deuterium labeled Terbuthylazine (HY-B1847). Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide. Terbuthylazine blocks electron transport in photosystem II via interaction with the D1-protein.
    Terbuthylazine-d<sub>9</sub>
  • HY-100427S
    Imazamox-13C,d3
    		99.63%
    Imazamox-13C,d3 is the 13C- and deuterium labeled Imazamox. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.
    Imazamox-<sup>13</sup>C,d<sub>3</sub>
  • HY-126987
    Mesosulfuron-methyl
    		Inhibitor 98.0%
    Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields.
    Mesosulfuron-methyl
  • HY-B1847R
    Terbuthylazine (Standard)
    Terbuthylazine (Standard) is the analytical standard of Terbuthylazine (HY-B1847). This product is intended for research and analytical applications. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide. Terbuthylazine blocks electron transport in photosystem II via interaction with the D1-protein.
    Terbuthylazine (Standard)
  • HY-126176
    Cloransulam-methyl
    		Inhibitor 99.44%
    Cloransulam-methyl is a triazolopyrimidine sulfonanilide herbicide. Cloransulam-methyl can be used to control broadleaf weeds in soybean by acetolactate synthase (ALS) inhibition.
    Cloransulam-methyl
  • HY-121727
    Triafamone
    		Inhibitor
    Triafamone (AE 1887196) is a paddy field pre-emergence and post-emergence sulfonamide herbicide. Triafamone weeds by inhibiting the acetolactate synthase (ALS) enzyme, thereby blocking the biosynthesis of branched-chain amino acids.
    Triafamone
  • HY-B1876R
    Nicosulfuron (Standard)
    Nicosulfuron (Standard) is the analytical standard of Nicosulfuron. This product is intended for research and analytical applications. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity.
    Nicosulfuron (Standard)
  • HY-B1847S1
    Terbuthylazine-d5
    		99.13%
    Terbuthylazine-d5 is the deuterium labeled Terbuthylazine (HY-B1847). Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide. Terbuthylazine blocks electron transport in photosystem II via interaction with the D1-protein.
    Terbuthylazine-d<sub>5</sub>
  • HY-W721637
    Foramsulfuron-d6
    Foramsulfuron-d6-1 is the deuterium labeled Foramsulfuron (HY-W422402). Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids.
    Foramsulfuron-d<sub>6</sub>
  • HY-B1876S
    Nicosulfuron-d6
    		98.4%
    Nicosulfuron-d6 is the deuterium labeled Nicosulfuron. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity.
    Nicosulfuron-d<sub>6</sub>